PREDICTION OF CROHN'S DISEASE RELAPSES AND THEIR PREVENTION

Abstract

The effectiveness of the developed method for predicting recurrence of CD in the postoperative period, due to the importance of including immunological criteria, allows increasing the sensitivity of the test by 3.5 times, specificity - by 1.9 times, and the prognostic value of the method - by 3.3 times. The use of the developed treatment and diagnostic algorithm for the prevention of recurrence of CD made it possible to reduce the frequency of its development in a mild form from 31% to 27.5%, in a moderate form from 21.4% to 12.5% and completely avoid its severe forms under the influence of pathogenetically substantiated differentiated and targeted anti-cytokine, hormonal and immunosuppressive therapy.